Eco-Friendly Bio-Fungicides Harnessing Weeds to Combat Phytophthora Capsici in Capsicum Annuum

Researchers are developing innovative bio-fungicides using extracts from weeds like Ageratum conyzoides and Parthenium hysterophorus to combat Phytophthora capsici, a major threat to bell pepper cultivation, while promoting sustainable agriculture.

Updated on: 23 December, 2024 10:16 AM IST By: Rajeev Kumar, School of Bioengineering & Biosciences, LPU, Punjab & Shweta Srivastava, School of Agriculture, LPU, Punjab
Bio-fungicides, derived from natural sources such as plant extracts and beneficial microorganisms, offer promising alternatives to synthetic fungicides.

In the quest for sustainable agricultural solutions, researchers have been exploring eco-friendly options to combat devastating plant pathogens. Among these, Phytophthora capsici has emerged as a particularly challenging pathogen, affecting a range of economically valuable crops, notably Capsicum annuum (bell pepper), worldwide. The pathogen causes severe blight and rot, leading to considerable yield losses. Given the harmful environmental impacts and resistance issues associated with conventional fungicides, our research team has turned to nature’s untapped resources weed plants to develop innovative biofungicides.

Why Bio-Fungicides?

Bio-fungicides, derived from natural sources such as plant extracts and beneficial microorganisms, offer promising alternatives to synthetic fungicides. They are typically biodegradable, less toxic to non-target organisms, and pose fewer risks to the environment and human health. In recent years, bio-fungicides have gained significant attention for their efficacy in managing various plant diseases while aligning with sustainable agriculture goals.

Targeting Phytophthora capsici: A Major Threat to Capsicum Cultivation

Phytophthora capsici is a soil-borne pathogen that thrives in warm and moist conditions, attacking the roots, stems, leaves, and fruits of Capsicum annuum. Traditional control methods have proven insufficient due to the pathogen’s adaptability and the growing resistance to synthetic chemicals. In response to these challenges, we have turned our attention to two invasive weed species with potential antifungal properties: Ageratum conyzoides and Parthenium hysterophorus.

Weed Plants as a Source of Bio-Fungicidal Agents

Weed plants are typically regarded as a nuisance, competing with crops for nutrients and water, and sometimes being toxic to livestock. However, certain weeds possess unique bioactive compounds that make them suitable for developing natural pesticides and fungicides. Specifically, Ageratum conyzoides and Parthenium hysterophorus are rich in secondary metabolites—natural compounds with antimicrobial properties that have shown potential for controlling a range of fungal pathogens.

Ageratum conyzoides: A Potent Antifungal Herb

Commonly known as billygoat-weed, Ageratum conyzoides is rich in essential oils, alkaloids, flavonoids, and other bioactive compounds. Previous studies have documented its antifungal and antibacterial properties, which are attributed primarily to its high content of bioactive compounds like precocene, ageratochromene, and other essential oils. These compounds disrupt fungal cell membranes and inhibit pathogen development, making them suitable candidates for controlling Phytophthora capsici in a natural and environmentally friendly way.

Parthenium hysterophorus: Transforming an Invasive Menace into an Agricultural Ally

Parthenium hysterophorus, also known as congress grass, is an invasive weed notorious for causing allergic reactions and outcompeting native vegetation. Despite its invasive nature, Parthenium contains an impressive array of phytochemicals, including sesquiterpene lactones, which are known to have strong antimicrobial properties. Our research has focused on harnessing these compounds for their antifungal potential, specifically targeting P. capsici in Capsicum annuum.

Developing a Novel Bio-Fungicide Formulation

Our study involved the extraction of leaf  components from Ageratum conyzoides and Parthenium hysterophorus  using environmentally friendly solvents. The resulting extracts were then tested for their efficacy against P. capsici under laboratory and greenhouse conditions. By optimizing the concentration of active compounds, we developed a bio-fungicidal formulation that not only inhibited the growth of P. capsici but also showed no adverse effects on the growth and yield of Capsicum annuum plants.

Preliminary results have shown promising outcomes, with the bio-fungicide demonstrating a comparable efficacy to some conventional fungicides. Moreover, the formulation has the advantage of being biodegradable and poses minimal risk to beneficial soil organisms, which are essential for maintaining soil health and nutrient cycling.

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